Description

4-Hydroxy-2-oxo-2H-chromene-3-carbonitrile is a versatile heterocyclic organic compound belonging to the coumarin family, specifically a 3-cyanocoumarin derivative. This high-purity intermediate is critical for synthesizing advanced pharmaceutical agents and functional organic materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in developing anticoagulant, anti-inflammatory, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides due to its bioactive coumarin core.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Fluorescent Dyes and Probes: Acts as a core structure for developing sensitive fluorescent sensors and biological imaging agents.
• Fine Chemical Synthesis: An important intermediate for creating complex molecules used in fragrances, cosmetics, and other specialty applications.
• Academic & Industrial Research: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	4-Hydroxy-2-oxo-2H-chromene-3-carbonitrile
CAS No.	10523-48-5
Molecular Formula	C10H5NO3
Molecular Weight	187.15 g/mol
Synonyms	3-Cyano-4-hydroxycoumarin; 4-Hydroxy-3-cyanocoumarin; 4-Hydroxycoumarin-3-carbonitrile; 3-Cyano-4-hydroxy-2H-chromen-2-one; 4-Hydroxy-2-oxo-2H-1-benzopyran-3-carbonitrile; 4-Hydroxy-2-oxo-2H-chromene-3-carbonitrile; 4-Hydroxy-3-cyano-2H-chromen-2-one
EINECS	234-070-9

Quality Control

Our 4-Hydroxy-2-oxo-2H-chromene-3-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	255 - 260 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.