Description

(2S,3S)-3-Methylpyrrolidine-2-Carboxylic Acid CAS NO 10512-89-7 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise three-dimensional structures. It is essential for research and development in the pharmaceutical industry, particularly for the synthesis of active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in the development of protease inhibitors and other targeted therapies.
• Peptidomimetic Research: Used to construct constrained peptide analogs and foldamers that mimic natural peptide structures for drug discovery.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to introduce defined stereocenters.
• Agrochemical Development: Potential intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme mechanisms and protein-protein interactions.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	(2S,3S)-3-Methylpyrrolidine-2-Carboxylic Acid
CAS No.	10512-89-7
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(2S,3S)-3-Methyl-2-pyrrolidinecarboxylic acid; (2S,3S)-3-Methylproline; cis-3-Methyl-L-proline; (2S,3S)-3-Methylpyrrolidine-2-carboxylic acid; L-cis-3-Methylproline; (2S,3S)-3-Methyl-2-carboxypyrrolidine; 3-Methyl-L-proline (cis); 10512-89-7
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-Methylpyrrolidine-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.