Description

4-Methylbenzenethiol, Sodium Salt is the sodium salt derivative of p-toluenethiol, a versatile organosulfur compound. This product is valued for its role as a key intermediate and reagent in advanced organic synthesis, particularly in the construction of sulfur-containing molecules and as a nucleophile in substitution reactions. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers requiring high-purity building blocks for active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of sulfur-containing active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides where the thiol moiety is incorporated for biological activity.
• Polymer & Material Science: Acts as a chain transfer agent (CTA) or modifier in polymerization processes and in the development of specialty polymers.
• Organic Synthesis Reagent: Employed as a nucleophilic thiolate source in alkylation, arylation, and Michael addition reactions.
• Ligand & Catalyst Preparation: Utilized in the preparation of metal-thiolate complexes and catalysts for various chemical transformations.
• Flavor & Fragrance Industry: May be used as a precursor in the synthesis of certain sulfur-based aroma compounds.

Basic Information

Product Name	4-Methylbenzenethiol, Sodium Salt
CAS No.	10486-08-5
Molecular Formula	C7H7NaS
Molecular Weight	146.18 g/mol
Synonyms	Sodium p-Toluenethiolate; Sodium 4-Methylbenzenethiolate; Sodium p-Methylbenzenethiolate; p-Toluenethiol Sodium Salt; 4-Methylbenzenethiol Sodium Salt; Sodium Thiocresolate; p-Thiocresol Sodium Salt; Sodium (4-Methylphenyl)thiolate
EINECS	234-002-9

Quality Control

Our 4-Methylbenzenethiol, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by titration or HPLC), identification (IR), and impurity profiling to ensure it meets stringent specifications for purity and consistency. Certificates of Analysis (COA) are provided with every shipment, documenting compliance with agreed-upon standards. We support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original packaging to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.