Description

Ethyl 4-Chlorocrotonate is a versatile organic ester building block characterized by its reactive chlorinated alkene and ester functionalities. This compound matters as a key intermediate in the synthesis of complex molecules, enabling the introduction of functionalized crotonate units. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a functionalized α,β-unsaturated ester moiety.
• Agrochemical Synthesis: Serves as a precursor in the production of herbicides, fungicides, and insecticides, where its reactive sites allow for structural diversification.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, Michael additions, and other cyclization processes to construct complex heterocyclic and carbocyclic frameworks.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	Ethyl 4-Chlorocrotonate
CAS No.	10479-85-3
Molecular Formula	C6H9ClO2
Molecular Weight	148.59 g/mol
Synonyms	Ethyl (E)-4-Chloro-2-butenoate; Ethyl trans-4-Chlorocrotonate; 4-Chlorocrotonic Acid Ethyl Ester; 2-Butenoic acid, 4-chloro-, ethyl ester, (E)-; Crotonic acid, 4-chloro-, ethyl ester; Ethyl γ-chlorocrotonate
EINECS	233-974-8

Quality Control

Our Ethyl 4-Chlorocrotonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (GC)	≥ 95.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.