Description

4-Hydroxy-2-(2-Hydroxyethyl)-2-Phenylbutyronitrile is a versatile bifunctional chemical intermediate featuring both hydroxyl and nitrile groups on a phenyl-substituted carbon chain. This unique structure makes it a valuable synthon for the production of complex molecules in advanced pharmaceutical and fine chemical synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing chiral centers and heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring chiral phenyl-ethanolamine or amino alcohol motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where its nitrile and alcohol functionalities allow for further derivatization.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic ligands used in catalysis.
• Polymer Chemistry: Can be utilized as a monomer or chain modifier in the synthesis of specialty polymers and resins, imparting specific polarity or reactivity.
• Research & Development: Employed in academic and industrial R&D labs for methodological studies in asymmetric synthesis and new reaction pathway exploration.

Basic Information

Product Name	4-Hydroxy-2-(2-Hydroxyethyl)-2-Phenylbutyronitrile
CAS No.	10469-27-9
Molecular Formula	C12H15NO2
Molecular Weight	205.25 g/mol
Synonyms	2-Phenyl-2-(2-hydroxyethyl)-4-hydroxybutyronitrile; 2-(2-Hydroxyethyl)-2-phenyl-4-hydroxybutyronitrile; 4-Hydroxy-2-(2-hydroxyethyl)-2-phenylbutanenitrile; α-(2-Hydroxyethyl)-α-phenyl-β-hydroxypropionitrile; 2-Phenyl-4-hydroxy-2-(2-hydroxyethyl)butyronitrile
EINECS	233-954-5

Quality Control

Our 4-Hydroxy-2-(2-Hydroxyethyl)-2-Phenylbutyronitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.