Description

Methylsulfamoyl Chloride is a versatile and highly reactive organosulfur compound primarily used as a key sulfamoylating reagent in organic synthesis. Its value lies in its ability to efficiently introduce the methylsulfamoyl functional group, a critical building block for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is instrumental in developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides that incorporate sulfamoyl moieties for enhanced activity.
• Chemical Research & Development: Serves as a fundamental reagent in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialty dyes and functional pigments requiring sulfonamide linkages.
• Polymer Modification: Acts as a functionalizing agent to introduce sulfamoyl groups into polymer chains, altering their physical and chemical properties.

Basic Information

Product Name	Methylsulfamoyl Chloride
CAS No.	10438-96-7
Molecular Formula	CH4ClNO2S
Molecular Weight	129.56 g/mol
Synonyms	Methanesulfonyl chloride, amide; N-Chloromethanesulfonamide; Methylaminosulfonyl chloride; Methanesulfonamide, N-chloro-; NSC 403058; Methanesulfonochloramide; Chloro(methylsulfonyl)amine
EINECS	233-937-9

Quality Control

Our Methylsulfamoyl Chloride is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to verify identity and potency. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation and moisture absorption. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.48 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.