Description

6-Chloroflavone is a halogenated derivative of the flavone core structure, a key scaffold in medicinal chemistry and organic synthesis. This compound is valued for its role as a versatile synthetic intermediate and a pharmacologically active building block. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and advanced organic materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and neurological disorders.
• Biochemical Research: Used as a reference standard or probe compound in studies investigating enzyme inhibition, receptor binding, and cellular signaling pathways.
• Organic Synthesis Building Block: The chlorinated flavone structure is employed in cross-coupling reactions and further functionalization to create complex heterocyclic libraries for high-throughput screening.
• Material Science Research: Investigated for its potential application in the development of organic semiconductors, fluorescent dyes, and photostable materials due to its conjugated aromatic system.
• Agrochemical Development: Explored as a lead structure for the synthesis of new pesticides and herbicides with enhanced biological activity.

Basic Information

Product Name	6-Chloroflavone
CAS No.	10420-73-2
Molecular Formula	C15H9ClO2
Molecular Weight	256.68 g/mol
Synonyms	6-Chloro-2-phenyl-4H-chromen-4-one; 6-Chloro-2-phenyl-4H-1-benzopyran-4-one; 6-Chloro-2-phenylchromone; Flavone, 6-chloro-; 2-Phenyl-6-chlorochromone; 6-Chlor-2-phenyl-chromon (German); 6-クロロフラボン (Japanese)
EINECS	233-903-1

Quality Control

Our 6-Chloroflavone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.