Description

2-Bromo-2-Methylpropiophenone is a versatile organic intermediate characterized by its brominated α-carbonyl structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for constructing molecular frameworks.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring a brominated ketone moiety for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where it serves as a building block for bioactive molecules.
• Organic Synthesis Reagent: Employed in laboratories for introducing the 2-bromo-2-methylpropiophenone group into target molecules via alkylation or as a starting material for heterocyclic chemistry.
• Photoinitiator Research: Investigated as a potential component or precursor in the development of photoinitiator systems for UV-curable coatings and inks.
• Ligand and Catalyst Development: Serves as a starting material for the synthesis of specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable compound for methodological studies and scale-up process development in university and corporate research settings.

Basic Information

Product Name	2-Bromo-2-Methylpropiophenone
CAS No.	10409-54-8
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	2-Bromo-2-methylpropiophenone; Phenacyl bromide, 2-methyl-; α-Bromoisobutyrophenone; 2-Bromo-2-methyl-1-phenyl-1-propanone; 1-Phenyl-2-bromo-2-methyl-1-propanone; 2-Methyl-2-bromopropiophenone; BIMK; 2-Bromo-2-methylpropionphenone
EINECS	233-877-8

Quality Control

Our 2-Bromo-2-Methylpropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	47 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.