Description

Propylsulfamoyl Chloride is a versatile organosulfur reagent primarily used as a key building block in organic synthesis. Its value lies in its role as a sulfamoylating agent, enabling the introduction of the sulfamoyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of novel herbicides and fungicides that incorporate sulfamoyl moieties for enhanced activity.
• Chemical Research & Development: Serves as a fundamental reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific sulfonamide linkages.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions to create complex sulfonamides.

Basic Information

Product Name	Propylsulfamoyl Chloride
CAS No.	10305-42-7
Molecular Formula	C₃H₈ClNO₂S
Molecular Weight	157.62 g/mol
Synonyms	1-Propanesulfonamide, N-chloro-; N-Chloropropanesulfonamide; Propylsulfonyl Chloride Amide; Propane-1-sulfonamoyl chloride; 1-Propylsulfamoyl chloride; Propanesulfonamoyl chloride; Sulfamoyl chloride, propyl-
EINECS	233-690-4

Quality Control

Our Propylsulfamoyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition from moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.