Description

α-Chlorofumaric acid diethyl ester is a versatile and reactive chlorinated fumarate derivative, serving as a key synthetic intermediate in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both an activated alkene and an ester group, which facilitates a range of chemical transformations, including Michael additions and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity building blocks for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactive chlorofumarate core.
• Organic Synthesis Reagent: Employed in Michael addition reactions, Diels-Alder reactions, and as a precursor for heterocyclic compounds in academic and industrial R&D.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials with tailored properties.
• Chemical Research: Serves as a standard or starting material in methodological studies and the development of new synthetic pathways in organic chemistry.

Basic Information

Product Name	α-Chlorofumaric acid diethyl ester
CAS No.	10302-94-0
Molecular Formula	C8H11ClO4
Molecular Weight	206.62 g/mol
Synonyms	Diethyl 2-chlorofumarate; (E)-Diethyl 2-chlorobut-2-enedioate; 2-Chlorofumaric Acid Diethyl Ester; Chlorofumaric Acid Diethyl Ester; Ethyl 2-Chlorofumarate; Fumaric acid, 2-chloro-, diethyl ester; NSC 403697; Diethyl (E)-2-chloro-2-butenedioate
EINECS	233-679-6

Quality Control

Our α-Chlorofumaric acid diethyl ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.