Description

5-o-Benzoyl-1,2-o-Isopropylidene-3-o-Methyl-α-D-Ribofuranose is a key protected ribofuranose derivative, a crucial chiral building block in organic synthesis. Its value lies in providing a versatile, selectively protected sugar scaffold for the controlled construction of complex nucleoside analogs and other bioactive molecules. This intermediate is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on antiviral, anticancer, and nucleotide-based therapeutics.

Application

• Nucleoside & Nucleotide Synthesis: A fundamental chiral precursor for the synthesis of modified nucleosides and nucleotides, including potential antiviral and anticancer agents.
• Pharmaceutical Intermediates: Serves as a critical building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D to study glycosylation reactions and develop new synthetic methodologies for complex sugars.
• Oligonucleotide Synthesis: Acts as a protected monomer or intermediate in the preparation of modified oligonucleotides for diagnostic and therapeutic applications.
• Glycoconjugate Development: Employed in the synthesis of glycoconjugates, which are important for vaccine development and studying biological recognition processes.

Basic Information

Product Name	5-o-Benzoyl-1,2-o-Isopropylidene-3-o-Methyl-α-D-Ribofuranose
CAS No.	10300-20-6
Molecular Formula	C16H20O6
Molecular Weight	308.33 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-methyl-5-O-benzoyl-α-D-ribofuranose; 3-O-Methyl-1,2-O-isopropylidene-5-O-benzoyl-α-D-ribofuranose; 5-O-Benzoyl-1,2-O-isopropylidene-3-O-methyl-α-D-ribofuranose; 3-O-Methyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose; 1,2-O-Isopropylidene-3-O-methyl-α-D-ribofuranose 5-benzoate; Protected 3-O-Methyl Ribofuranose
EINECS	Contact for details

Quality Control

Our 5-o-Benzoyl-1,2-o-Isopropylidene-3-o-Methyl-α-D-Ribofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation analysis, to ensure high chemical purity and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.