Description

1-Chloro-4-Iodobutane is a versatile bifunctional alkyl halide building block of significant importance in organic synthesis. Its distinct structure, featuring reactive chloro and iodo termini, makes it a valuable precursor for constructing complex molecular frameworks through nucleophilic substitution and cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs) and heterocyclic compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating advanced functional materials used in displays and electronics.
• Cross-Coupling Reactions: The iodo group is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Heck, Sonogashira) for carbon-carbon bond formation.
• Polymer & Dendrimer Chemistry: Employed as a linker or spacer unit in the synthesis of specialty polymers and dendritic structures.
• Organic Synthesis Reagent: Utilized for alkylation reactions and the introduction of butylene chains with different terminal functionalities.

Basic Information

Item	Detail
Product Name	1-Chloro-4-Iodobutane
CAS No.	10297-05-9
Molecular Formula	C4H8ClI
Molecular Weight	218.46 g/mol
Synonyms	4-Chloro-1-iodobutane; 1-Iodo-4-chlorobutane; Butane, 1-chloro-4-iodo-; 4-Chlorobutyl iodide; ω-Chloro-ω'-iodobutane; NSC 60545; γ-Chloro-ω-iodobutane
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Iodobutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	~1.8 g/mL
Refractive Index (n20D)	~1.55
Related Substances (GC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.