Description

Ketone, 1-Indanyl Methyl, (R)-(-)- (8Ci) is a high-purity chiral ketone building block, distinguished by its specific (R)-(-) enantiomeric configuration. This compound is critical for the synthesis of complex molecules where stereochemistry dictates biological activity and material properties. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and advanced materials sectors, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile precursor in stereoselective reactions, including asymmetric reductions and nucleophilic additions, to construct complex chiral centers.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for applications in homogeneous catalysis and enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Academic and R&D: A valuable reference standard and starting material for methodological development in synthetic organic chemistry and medicinal chemistry research.

Basic Information

Product Name	Ketone, 1-Indanyl Methyl, (R)-(-)- (8Ci)
CAS No.	10277-73-3
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	(R)-(-)-1-Indanyl Methyl Ketone; (R)-1-(2,3-Dihydro-1H-inden-1-yl)ethanone; (R)-α-Methyl-1-indanone; (R)-1-Acetylindane; (R)-(-)-1-Acetylindane; (R)-1-Indanone, 2-methyl-; (R)-2-Methyl-1-indanone; (R)-(-)-2-Methylindan-1-one
EINECS	Contact for details

Quality Control

Our Ketone, 1-Indanyl Methyl, (R)-(-)- (8Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, and impurities is supplied with every shipment to guarantee consistency and traceability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.