Description

4-Acetylphenylacetonitrile is a versatile aromatic nitrile building block characterized by its acetyl and nitrile functional groups. This compound is of significant value in advanced organic synthesis, serving as a key precursor for the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those containing fused heterocyclic systems like indoles, quinolines, and isoquinolines.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create complex molecular architectures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes, including asymmetric synthesis.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and advanced polymers due to its rigid aromatic core and functional handles.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring specific aromatic nitrile backbones.

Basic Information

Product Name	4-Acetylphenylacetonitrile
CAS No.	10266-42-9
Molecular Formula	C10H9NO
Molecular Weight	159.18 g/mol
Synonyms	4-Acetylbenzyl cyanide; 2-(4-Acetylphenyl)acetonitrile; p-Acetylphenylacetonitrile; 4-Acetylbenzeneacetonitrile; 4-Acetyl-α-tolunitrile; (4-Acetylphenyl)acetonitrile; 4-Acetylbenzyl nitrile; 1-[4-(Cyanomethyl)phenyl]ethanone
EINECS	Contact for details

Quality Control

Our 4-Acetylphenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.