Description

(R,9Z,11E)-13-Hydroxy-9,11-Octadecadienoic Acid Methyl Ester is a high-purity, stereospecific methyl ester derivative of a conjugated hydroxy fatty acid. This compound serves as a critical chiral intermediate and reference standard in advanced organic synthesis and analytical research. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise molecular building blocks for developing bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, leukotrienes, and other bioactive lipid mediators.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving lipoxygenases and other lipid-metabolizing enzymes.
• Agrochemical Development: Serves as a precursor in the creation of novel plant growth regulators and signaling molecule analogs.
• Specialty Chemical Synthesis: Employed in the production of advanced materials, surfactants, and lubricants where specific stereochemistry is required.
• Analytical Chemistry: Acts as a high-purity calibration standard for GC, HPLC, and LC-MS methods in lipidomics and metabolomics.

Basic Information

Product Name	(R,9Z,11E)-13-Hydroxy-9,11-Octadecadienoic Acid Methyl Ester
CAS No.	10219-70-2
Molecular Formula	C₁₉H₃₄O₃
Molecular Weight	310.47 g/mol
Synonyms	Methyl (R)-(9Z,11E)-13-Hydroxyoctadeca-9,11-dienoate; 13-Hydroxy-9,11-octadecadienoic acid, methyl ester, (9Z,11E,13R)-; (R)-Methyl 13-hydroxy-9Z,11E-octadecadienoate; 13-Hydroxy-9,11-linoleic acid methyl ester (stereospecific); (9Z,11E,13R)-13-Hydroxyoctadeca-9,11-dienoic acid methyl ester; Conjugated linoleic acid derivative methyl ester; 13-HODE methyl ester (R-isomer)
EINECS	Contact for details

Quality Control

Our production of (R,9Z,11E)-13-Hydroxy-9,11-Octadecadienoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We maintain GMP-compliant documentation practices suitable for use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee (R-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.