Description

4-Phenylpyrazole is a versatile heterocyclic organic compound that serves as a crucial building block in advanced chemical synthesis. Its unique pyrazole core fused with a phenyl ring makes it a valuable intermediate for developing pharmaceuticals, agrochemicals, and functional materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of modern pesticides and herbicides, where the pyrazole moiety contributes to biological activity.
• Ligand in Catalysis: Serves as a precursor for nitrogen-donor ligands in transition metal catalysis, enabling various coupling and transformation reactions.
• Material Science Research: Investigated as a building block for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probe: Utilized in the design of molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	4-Phenylpyrazole
CAS No.	10199-68-5
Molecular Formula	C9H8N2
Molecular Weight	144.17 g/mol
Synonyms	4-Phenyl-1H-pyrazole; 1H-Pyrazole, 4-phenyl-; 4-Phenylpyrazol; Pyrazole, 4-phenyl-; NSC 406916; 4-Phenyl-1H-pyrazol; 4-Phenylpyrazole (major); 4-Phenyl-1H-pyrazole (9CI)
EINECS	Contact for details

Quality Control

Our 4-Phenylpyrazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	128 - 132 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.