Description

Diethyl 3-Bromopropylmalonate is a versatile brominated malonate ester, a key building block in organic synthesis. Its value lies in its reactive bromine and malonate functional groups, enabling efficient carbon-carbon bond formation and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, serving as a critical intermediate for synthesizing complex molecules, heterocycles, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing cyclopropane or other constrained ring systems.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where specific alkylation or cyclization steps are required.
• Organic Synthesis Building Block: Employed in classic malonate chemistry for alkylation reactions, Knoevenagel condensations, and the synthesis of carboxylic acids, ketones, and esters.
• Heterocyclic Chemistry: Serves as a starting material for the construction of nitrogen- and oxygen-containing heterocycles, which are prevalent in many bioactive compounds.
• Material Science Research: Utilized in the development of novel polymers, ligands, and functional organic materials that require specific bromo-ester functionalities.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	Diethyl 3-Bromopropylmalonate
CAS No.	10149-21-0
Molecular Formula	C10H17BrO4
Molecular Weight	281.15 g/mol
Synonyms	3-Bromopropylmalonic Acid Diethyl Ester; Diethyl (3-Bromopropyl)malonate; Diethyl 3-Bromopropymalonate; Malonic Acid, (3-Bromopropyl)-, Diethyl Ester; Ethyl 3-Bromopropylmalonate; (3-Bromopropyl)propanedioic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 3-Bromopropylmalonate is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.458 - 1.462
Specific Gravity	1.30 - 1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.