Description

1-Propanesulfonyl Chloride is a key organosulfur reagent widely used as a versatile sulfonylation agent in organic synthesis. Its primary value lies in its ability to introduce the propanesulfonyl group, a crucial step in creating sulfonamides and other functionalized molecules with specific properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A vital reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents that require sulfonyl functional groups.
• Polymer Modification: Acts as a functionalizing agent to introduce sulfonyl chloride groups into polymer chains for specialty materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of sulfonated dyes and colorants.
• Chemical Research & Development: A fundamental tool in medicinal chemistry and process chemistry for probing structure-activity relationships and scaling up novel compounds.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-Propanesulfonyl Chloride
CAS No.	10147-36-1
Molecular Formula	C3H7ClO2S
Molecular Weight	142.60 g/mol
Synonyms	Propane-1-sulfonyl chloride; 1-Propanesulfonic acid chloride; Propanesulfonyl chloride; n-Propylsulfonyl chloride; NSC 401119; Propylsulfonyl chloride; 1-Propylsulfonyl chloride
EINECS	233-410-7

Quality Control

Our 1-Propanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by titration or GC), identity confirmation (IR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are kept tightly sealed in a dry environment. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.