Description

2,2,3,3,3-Pentafluoro-1-(p-Tolyl)Propane-1-One is a high-value fluorinated aromatic ketone building block, distinguished by its unique combination of a p-tolyl group and a pentafluoropropanone moiety. This structure is critical for introducing lipophilicity and metabolic stability in advanced chemical synthesis, making it a sought-after intermediate for research and development. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical manufacturers engaged in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for high-performance liquid crystal displays (LCDs).
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials.
• Advanced Polymer Modification: Acts as a functional monomer or cross-linking agent to impart specific chemical resistance and surface properties to polymers.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	2,2,3,3,3-Pentafluoro-1-(p-Tolyl)Propane-1-One
CAS No.	10116-95-7
Molecular Formula	C10H7F5O
Molecular Weight	238.16 g/mol
Synonyms	1-(4-Methylphenyl)-2,2,3,3,3-pentafluoro-1-propanone; p-Tolyl Pentafluoroethyl Ketone; 4-Methyl-2',2',3',3',3'-pentafluoropropiophenone; 2,2,3,3,3-Pentafluoro-1-(4-methylphenyl)-1-propanone; α,α,β,β,β-Pentafluoro-4-methylpropiophenone; Pentafluoroethyl 4-Tolyl Ketone; 4-Methyl-α,α,β,β,β-pentafluoropropiophenone
EINECS	Contact for details

Quality Control

Our 2,2,3,3,3-Pentafluoro-1-(p-Tolyl)Propane-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.