Description

(3R)-4β-Acetoxy-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-3,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5-Dione is a complex, high-purity sesquiterpene lactone derivative with a defined stereochemistry, serving as a critical advanced intermediate in organic synthesis. This compound matters for its role in constructing intricate molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities. CAS No. 10092-04-3.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex natural product analogs and potential therapeutic agents.
• Organic Synthesis Research: Used in academic and industrial R&D for studying cycloaddition reactions, stereoselective transformations, and total synthesis projects.
• Agrochemical Development: Serves as a precursor for creating novel bioactive compounds with potential herbicidal or insecticidal properties.
• Fine Chemical Production: Intermediate in the manufacture of specialty flavors, fragrances, and high-value performance chemicals.
• Material Science: Potential monomer or cross-linking agent for developing specialized polymers with unique thermal or mechanical properties.

Basic Information

Item	Detail
Product Name	(3R)-4β-Acetoxy-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-3,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5-Dione
CAS No.	10092-04-3
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	4β-Acetoxy-3,3aα,4,4a,7aα,8,9,9aβ-octahydro-3,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5-dione; 4β-Acetoxy-3,3aα,4,4a,7aα,8,9,9aβ-octahydro-3,4aβ,8α-trimethylazuleno[6,5-b]furan-2,5-dione, (3R)-; Alantolactone acetate derivative; Isoalantolactone acetate; Helenalin analog intermediate
EINECS	Contact for details

Quality Control

Our (3R)-4β-Acetoxy-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-3,4Aβ,8α-Trimethylazuleno[6,5-B]Furan-2,5-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for advanced synthetic applications. Certificates of Analysis (COA) with full chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.