Description

3,3,3-Trifluoro-Dl-Alanine is a non-natural, fluorinated amino acid derivative of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl group, which imparts enhanced metabolic stability, lipophilicity, and electronic properties to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, peptide modification, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated analogs of peptides and small molecule drugs to improve bioavailability and metabolic resistance.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atoms can enhance activity and environmental persistence.
• Biochemical Probe Development: Incorporated into peptides and proteins as a stable, non-natural amino acid to study protein structure, function, and interactions via 19F NMR spectroscopy.
• Material Science: Serves as a precursor for specialty polymers and coatings where fluorine content is desired for properties like chemical resistance and low surface energy.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore the impact of fluorination on drug potency and selectivity.
• Radiopharmaceuticals: Potential precursor for the synthesis of fluorine-18 labeled compounds used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	3,3,3-Trifluoro-Dl-Alanine
CAS No.	10065-69-7
Molecular Formula	C3H4F3NO2
Molecular Weight	143.06 g/mol
Synonyms	DL-3,3,3-Trifluoroalanine; 2-Amino-3,3,3-trifluoropropanoic acid; 3,3,3-Trifluoro-DL-alanine; (±)-3,3,3-Trifluoroalanine; α-Amino-beta,beta,β-trifluoropropionic acid; 3,3,3-Trifluoro-2-aminopropanoic acid; NSC 92359; Trifluoroalanine
EINECS	233-200-8

Quality Control

Our 3,3,3-Trifluoro-Dl-Alanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.