Description

Lofenal CAS NO 10047-08-2 is a specialized chemical compound, also known as 4-Fluorobenzyl chloride, serving as a critical fluorinated building block in advanced organic synthesis. Its value lies in enabling the introduction of the 4-fluorobenzyl moiety, a key structural feature that can enhance the biological activity and metabolic stability of target molecules. This high-purity intermediate is essential for research and production within the pharmaceutical and agrochemical industries, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display technologies.
• Organic Synthesis: A versatile reagent for introducing the 4-fluorobenzyl protecting group or functional handle in complex molecule construction.
• Dye and Pigment Industry: Employed in the synthesis of specialized fluorinated dyes with unique colorfastness and properties.
• Polymer Modification: Used to create fluorinated monomers for specialty polymers with enhanced chemical resistance and performance.

Basic Information

Product Name	Lofenal
CAS No.	10047-08-2
Molecular Formula	C7H6ClF
Molecular Weight	144.57 g/mol
Synonyms	4-Fluorobenzyl chloride; 1-(Chloromethyl)-4-fluorobenzene; α-Chloro-4-fluorotoluene; p-Fluorobenzyl chloride; (4-Fluorophenyl)methyl chloride; 4-Fluorobenzylchloride; 4-Fluoro-benzylchlorid; Lofenal (trade name)
EINECS	233-155-1

Quality Control

Our Lofenal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment, ensuring full traceability and compliance with your procurement standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	1.18 - 1.22 g/cm³ @ 20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.