Description

Calcium β-Hydroxy-β-Methylbutyrate is the calcium salt of the leucine metabolite HMB, a key compound in muscle protein metabolism. This high-purity ingredient is essential for formulating dietary supplements and clinical nutrition products aimed at supporting muscle mass, strength, and recovery. It is primarily required by manufacturers in the global nutraceutical, sports nutrition, and functional food industries seeking a stable, bioavailable source of HMB.

Application

• Sports Nutrition & Dietary Supplements: A core ingredient in powders, capsules, and ready-to-drink formulations designed to enhance muscle synthesis, reduce exercise-induced muscle damage, and improve athletic performance.
• Clinical & Medical Nutrition: Used in specialized enteral formulas and medical foods to address muscle wasting (sarcopenia, cachexia) in elderly, post-surgical, or chronically ill patients.
• Functional Food & Beverage Fortification: Incorporated into protein bars, shakes, and meal replacement products to add a muscle-support functional claim.
• Animal Nutrition (Feed Additives): Applied in premium livestock and aquaculture feed to promote lean muscle growth, feed efficiency, and overall animal health.
• Pharmaceutical Intermediates: Serves as a key starting material or active pharmaceutical ingredient (API) in the development of metabolic and musculoskeletal health drugs.

Basic Information

Product Name	Calcium β-Hydroxy-β-Methylbutyrate
CAS No.	135236-72-5
Molecular Formula	C10H18CaO6
Molecular Weight	274.33 g/mol
Synonyms	Calcium HMB; Calcium β-hydroxy-β-methylbutyrate; HMB-Ca; Calcium 3-hydroxy-3-methylbutanoate; (3-Hydroxy-3-methylbutanoato)calcium; 3-Hydroxy-3-methylbutyric acid calcium salt; β-Hydroxy-β-methylbutyric acid calcium salt; HMB Calcium Monohydrate
EINECS	Contact for details

Quality Control

Our Calcium β-Hydroxy-β-Methylbutyrate is manufactured under strict quality management systems. We offer grades compliant with relevant standards for dietary supplements and food ingredients. Every batch is supported by a comprehensive Certificate of Analysis (COA) verifying identity, purity, and safety parameters. Our rigorous quality testing ensures the product meets stringent specifications for heavy metals, microbiological limits, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can lead to caking or degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HMB-Ca, anhydrous basis)	≥ 98.0 %
pH (10% solution)	7.0 - 9.0
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Arsenic (As)	≤ 3 ppm
Residual Solvents	Complies with ICH Q3C
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
E. Coli	Negative
Salmonella	Negative

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.