Description

Ethyl (Z)-3-Iodoprop-2-Enoate is a versatile iodinated α,β-unsaturated ester, a key building block in organic synthesis. Its value lies in its ability to participate in cross-coupling reactions and serve as a Michael acceptor, enabling the construction of complex molecular frameworks. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring stereoselective introduction of functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and liquid crystals.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Heck, Stille, and Suzuki-Miyaura couplings to form new carbon-carbon bonds.
• Conjugate Addition (Michael Addition): The electron-deficient alkene readily undergoes nucleophilic addition, facilitating the synthesis of complex organic molecules.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.

Basic Information

Product Name	Ethyl (Z)-3-Iodoprop-2-Enoate
CAS No.	10021-64-4
Molecular Formula	C5H7IO2
Molecular Weight	226.01 g/mol
Synonyms	(Z)-Ethyl 3-iodoacrylate; Ethyl (Z)-3-iodoacrylate; Ethyl (Z)-3-iodoprop-2-enoate; (Z)-3-Iodoacrylic Acid Ethyl Ester; (Z)-3-Iodoprop-2-enoic Acid Ethyl Ester; (Z)-β-Iodoacrylic Acid Ethyl Ester; Ethyl cis-3-iodoacrylate
EINECS	233-018-6

Quality Control

Our Ethyl (Z)-3-Iodoprop-2-Enoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-isomer, GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.