Description

(S)-Hydroxy(2-Furanyl)Acetonitrile is a high-value chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in the presence of both a reactive nitrile group and a stereogenic center, enabling the construction of complex, optically active molecules. This compound is primarily needed by research and development laboratories, pharmaceutical companies, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in the development of antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products containing furan or tetrahydrofuran moieties.
• Fine Chemical Manufacturing: A building block for creating specialty chemicals, flavors, and fragrances requiring high optical purity.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or organic electronic materials.

Basic Information

Product Name	(S)-Hydroxy(2-Furanyl)Acetonitrile
CAS No.	10017-07-9
Molecular Formula	C7H5NO2
Molecular Weight	135.12 g/mol
Synonyms	(S)-2-Furylglycolonitrile; (S)-α-Hydroxy-2-furanacetonitrile; (S)-2-Hydroxy-2-(2-furyl)acetonitrile; (S)-Hydroxy(furan-2-yl)acetonitrile; (2S)-2-Hydroxy-2-(furan-2-yl)acetonitrile; (S)-Furylglycolonitrile; (S)-Furan-2-yl(hydroxy)acetonitrile; (S)-Furan-2-ylglycolonitrile
EINECS	Contact for details

Quality Control

Our (S)-Hydroxy(2-Furanyl)Acetonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high optical purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and impurity profile is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend maintaining the product at 2-8°C under an inert atmosphere to preserve its chemical integrity and optical purity. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.