Description

(R)-2-(Benzo[D][1,3]Dioxol-5-Yl)-2-Hydroxyacetonitrile is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its value lies in its enantiomerically pure (R)-configuration and functional groups, which are crucial for constructing complex molecules with specific stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of potential new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can be critical for biological activity and environmental safety.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and other specialty chemicals requiring high stereochemical purity.
• Academic & R&D Laboratories: Utilized in methodological studies and for the preparation of reference standards in chemical and biochemical research.

Basic Information

Product Name	(R)-2-(Benzo[D][1,3]Dioxol-5-Yl)-2-Hydroxyacetonitrile
CAS No.	10017-05-7
Molecular Formula	C9H7NO3
Molecular Weight	177.16 g/mol
Synonyms	(R)-Piperonyl cyanohydrin; (R)-2-Hydroxy-2-(1,3-benzodioxol-5-yl)acetonitrile; (R)-1,3-Benzodioxole-5-glycolonitrile; (R)-Benzo[1,3]dioxol-5-yl(hydroxy)acetonitrile; (R)-Mandelonitrile, 3,4-(methylenedioxy)-; (R)-α-Hydroxypiperonylacetonitrile; (R)-Form of Piperonyl Cyanohydrin
EINECS	Contact for details

Quality Control

Our (R)-2-(Benzo[D][1,3]Dioxol-5-Yl)-2-Hydroxyacetonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (R-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.