Description

Cannabidiol-3-Monomethyl Ether is a synthetic derivative of cannabidiol (CBD), characterized by the methylation of the phenolic hydroxyl group. This modification enhances its stability and alters its pharmacological profile, making it a valuable reference standard and research chemical for exploring cannabinoid structure-activity relationships. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and analytical chemistry sectors for method development, bioactivity screening, and as a key intermediate in synthetic pathways.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and analytical marker for the identification and quantification of cannabinoid derivatives in drug discovery pipelines.
• Bioactivity & Mechanism Studies: Used in preclinical research to investigate the pharmacological effects, metabolic pathways, and receptor binding profiles of modified cannabinoids.
• Analytical Method Development: Essential for calibrating instruments and validating analytical methods (e.g., HPLC, GC-MS, LC-MS) in quality control and forensic laboratories.
• Chemical Synthesis Intermediate: Acts as a key building block or precursor in the synthesis of novel cannabinoid analogs for further biological evaluation.
• Academic & Institutional Research: Supports fundamental chemical and biological studies in universities and research institutes focused on medicinal chemistry and neuropharmacology.

Basic Information

Product Name	Cannabidiol-3-Monomethyl Ether
CAS No.	1972-05-0
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	CBD 3-Monomethyl Ether; 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol methyl ether; Cannabidiol 3-methyl ether; O-Methylcannabidiol; 5-Pentyl-2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]benzene-1,3-diyl dimethyl ether (isomeric form).
EINECS	Contact for details

Quality Control

Our Cannabidiol-3-Monomethyl Ether is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert gas purging to minimize oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.