Description

(E)-2-Butene-1,4-Diol Di(Methanesulfonate) CAS NO 1953-56-6 is a high-purity, bifunctional mesylate ester derivative of (E)-2-butene-1,4-diol, serving as a critical pharmaceutical intermediate and versatile chemical building block. Its primary value lies in its ability to act as a key electrophile in alkylation reactions and as a precursor for synthesizing complex molecules, including active pharmaceutical ingredients (APIs) and specialty polymers. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in anticancer and antiviral drug development.
• Alkylating Agent: Used in organic synthesis to introduce the (E)-2-butene-1,4-diyl moiety into target molecules via nucleophilic substitution reactions.
• Cross-linking Agent: Employed in polymer chemistry to create cross-linked networks for specialty resins, coatings, and hydrogels.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a tool compound for modifying biomolecules and studying biological pathways.
• Material Science Research: Precursor for developing novel organic electronic materials and liquid crystals.

Basic Information

Product Name	(E)-2-Butene-1,4-Diol Di(Methanesulfonate)
CAS No.	1953-56-6
Molecular Formula	C6H12O6S2
Molecular Weight	244.28 g/mol
Synonyms	(E)-But-2-ene-1,4-diyl bis(methanesulfonate); trans-2-Butene-1,4-diol Dimethanesulfonate; 1,4-Bis(methanesulfonyloxy)-2-butene (trans); (E)-1,4-Bis(methylsulfonyloxy)-2-butene; trans-1,4-Bis(methanesulphonyloxy)but-2-ene; (E)-2-Butenediyl Dimethanesulfonate; BOS 922; NSC 82196
EINECS	217-810-6

Quality Control

Our (E)-2-Butene-1,4-Diol Di(Methanesulfonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.