Description

3'-Trifluoromethylisobutyranilide is a specialized fluorinated anilide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a fluorinated building block for creating advanced electronic and optoelectronic materials.
• Organic Synthesis & Catalysis: A versatile reagent for constructing complex molecules in medicinal chemistry and material science research programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds under cGMP or research-grade conditions.

Basic Information

Product Name	3'-Trifluoromethylisobutyranilide
CAS No.	1939-27-1
Molecular Formula	C11H12F3NO
Molecular Weight	231.22 g/mol
Synonyms	N-(3-(Trifluoromethyl)phenyl)isobutyramide; 3'-(Trifluoromethyl)isobutyranilide; 2-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide; α,α-Dimethyl-3-trifluoromethylacetanilide; Isobutyric acid 3-trifluoromethylanilide; m-Trifluoromethylisobutyranilide; 3-Trifluoromethylphenylisobutyramide
EINECS	217-719-5

Quality Control

Our 3'-Trifluoromethylisobutyranilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with consistent quality, from research-grade to cGMP-compliant material as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	97 - 101 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.