Description

1-Chloro-5-Isocyano-2,4-Dimethoxybenzene is a versatile aromatic building block characterized by its reactive isocyano and chloro substituents. This compound is valued for its role as a key intermediate in the synthesis of complex heterocyclic and pharmaceutical compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with benzimidazole or other nitrogen-containing heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and polymers where its electron-donating methoxy groups and reactive handles are beneficial.
• Chemical Biology Probes: Utilized in the design of activity-based probes and bioconjugation reagents due to the high reactivity of the isocyano group.

Basic Information

Product Name	1-Chloro-5-Isocyano-2,4-Dimethoxybenzene
CAS No.	1930-81-0
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	2,4-Dimethoxy-5-chlorophenyl isocyanide; 5-Chloro-2,4-dimethoxybenzene isocyanide; 5-Chloro-2,4-dimethoxyphenyl isocyanide; 5-Chloro-2,4-dimethoxybenzenisocyanid; 5-Chloro-2,4-dimethoxybenzenisocyanide; 1-Chloro-2,4-dimethoxy-5-isocyanobenzene; 5-Chloro-2,4-dimethoxy-1-isocyanobenzene; 5-Chloro-2,4-dimethoxyphenyl isonitrile
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Isocyano-2,4-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under subdued lighting where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.