Description

3,4,5-Trimethoxycinnamic Acid Ethyl Ester is a high-purity organic ester derivative of cinnamic acid, characterized by its trimethoxy substitution pattern. This compound serves as a versatile and valuable pharmaceutical intermediate and fine chemical building block for advanced synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and production of various drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in coupling reactions, esterifications, and as a starting material for complex molecule construction in medicinal chemistry.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and advanced organic materials.
• Biochemical Research: Used as a standard or reagent in biochemical studies and analytical method development.
• Academic & Industrial R&D: Serves as a critical compound for methodological studies and scale-up process development in chemical research.

Basic Information

Product Name	3,4,5-Trimethoxycinnamic Acid Ethyl Ester
CAS No.	1878-29-1
Molecular Formula	C14H18O5
Molecular Weight	266.29 g/mol
Synonyms	Ethyl 3,4,5-Trimethoxycinnamate; Ethyl (E)-3-(3,4,5-Trimethoxyphenyl)acrylate; 3,4,5-Trimethoxycinnamic Acid Ethyl Ester; (E)-Ethyl 3-(3,4,5-trimethoxyphenyl)propenoate; NSC 406170; Ethyl 3,4,5-Trimethoxycinnamate; Ethyl trans-3,4,5-Trimethoxycinnamate
EINECS	217-516-6

Quality Control

Our 3,4,5-Trimethoxycinnamic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.