Description

Trichloroacetic Acid tert-Butyl Ester is a versatile organic ester and a key reagent in advanced chemical synthesis. This compound matters for its role as a protected form of trichloroacetic acid, offering enhanced stability and controlled reactivity in demanding processes. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for applications such as peptide synthesis and the production of specialized intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Peptide Synthesis Reagent: Used as a protecting group or activating agent in solid-phase and solution-phase peptide chemistry.
• Agrochemical Manufacturing: Serves as a precursor in the production of herbicides, pesticides, and other crop protection agents.
• Organic Synthesis: Employed in laboratories and pilot plants for esterification reactions, acylations, and the introduction of the trichloroacetyl group.
• Polymer Chemistry: Acts as a modifier or initiator in the synthesis of specialized polymers and resins.
• Chemical Research: A valuable tool in methodological development and exploratory chemistry within academic and industrial R&D settings.

Basic Information

Product Name	Trichloroacetic Acid tert-Butyl Ester
CAS No.	1860-21-5
Molecular Formula	C6H9Cl3O2
Molecular Weight	219.49 g/mol
Synonyms	tert-Butyl Trichloroacetate; Trichloroacetic Acid tert-Butyl Ester; 2-Methyl-2-propyl Trichloroacetate; t-Butyl Trichloroacetate; Trichloroacetic Acid 1,1-Dimethylethyl Ester; TCA-t-Butyl Ester; (CH3)3COCOCCl3; 1,1-Dimethylethyl Trichloroacetate
EINECS	217-468-9

Quality Control

Our Trichloroacetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or HPLC and impurity profiling, to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, it should be stored separately from bases, oxidizing agents, and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.28 g/cm³
Refractive Index (n20D)	~1.435

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.