Description

4-Chlorophenylsulfonylacetonitrile is a versatile sulfonyl-based nitrile compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a sulfonyl and a nitrile group on a chlorinated aromatic ring, makes it a valuable building block for constructing complex molecules with specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactive sulfonyl moiety.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and cyano-group transformations to create diverse chemical libraries.
• Dye and Pigment Intermediate: Utilized in the production of specialized colorants and photographic chemicals.

Basic Information

Product Name	4-Chlorophenylsulfonylacetonitrile
CAS No.	1851-09-8
Molecular Formula	C8H6ClNO2S
Molecular Weight	215.66 g/mol
Synonyms	(4-Chlorophenyl)sulfonylacetonitrile; 4-Chlorobenzenesulfonylacetonitrile; p-Chlorophenylsulfonylacetonitrile; Acetonitrile, [(4-chlorophenyl)sulfonyl]-; 2-((4-Chlorophenyl)sulfonyl)acetonitrile; 1851-09-8; 4-Chlorobenzene-1-sulfonylacetonitrile; NSC 403119
EINECS	Contact for details

Quality Control

Our 4-Chlorophenylsulfonylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing all specification results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.