Description

Trifluoroacetic Acid 2,6-Dimethylphenyl Ester is a specialized fluorinated aromatic ester derived from trifluoroacetic acid and 2,6-dimethylphenol. This compound serves as a high-value building block and reagent in advanced organic synthesis, particularly where the introduction of a sterically hindered, electron-withdrawing aryloxy group is required. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, especially those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl and dimethylphenyl groups contribute to biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Polymer Modification: Employed to introduce fluorinated aromatic esters into polymer chains, altering physical properties like solubility, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: Functions as an acylating agent or a protecting group in multi-step synthetic routes for fine chemicals.
• Material Science Research: Used in the development of novel organic electronic materials and liquid crystals.

Basic Information

Product Name	Trifluoroacetic Acid 2,6-Dimethylphenyl Ester
CAS No.	1842-06-4
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	2,6-Dimethylphenyl Trifluoroacetate; 2,6-Xylyl Trifluoroacetate; Trifluoroacetic Acid 2,6-Xylyl Ester; 2,6-Dimethylphenyl Trifluoroethanoate; α,α,α-Trifluoro-2,6-dimethylphenyl Acetate; 2,6-Dimethylphenyl Ester of Trifluoroacetic Acid; 2,6-DMP-TFA Ester
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid 2,6-Dimethylphenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are kept tightly sealed to prevent moisture ingress and evaporation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.