Description

4-Cyanotetrahydropyran is a versatile heterocyclic nitrile compound that serves as a valuable building block in advanced organic synthesis. Its molecular structure, featuring both a cyano group and a tetrahydropyran ring, makes it a critical intermediate for constructing complex pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the tetrahydropyran moiety can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and other functional materials requiring specific heterocyclic architectures.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex organic molecules for clients.

Basic Information

Product Name	4-Cyanotetrahydropyran
CAS No.	1836-77-7
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	4-Cyanotetrahydropyran; Tetrahydropyran-4-carbonitrile; 4-Cyanotetrahydropyran-4-carbonitrile; 4-Pyrancarbonitrile, tetrahydro-; Tetrahydro-4-pyrancarbonitrile; 4-Cyanooxane; Oxane-4-carbonitrile
EINECS	217-405-9

Quality Control

Our 4-Cyanotetrahydropyran is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.