Description

Azidoacetic Acid Methyl Ester is a versatile organic azide compound, primarily valued as a key click chemistry reagent and a crucial building block in organic synthesis. Its high reactivity, particularly in Huisgen 1,3-dipolar cycloaddition reactions, makes it indispensable for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to introduce azide functional groups for further derivatization.

Application

• Click Chemistry Reagent: A fundamental component for Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) to create 1,2,3-triazole linkages.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, enabling the attachment of bioactive molecules.
• Peptide and Bioconjugation Chemistry: Facilitates the site-specific labeling and modification of peptides, proteins, and other biomolecules.
• Polymer and Materials Science: Serves as a monomer or cross-linking agent for creating functional polymers, hydrogels, and advanced materials with tailored properties.
• Agrochemical Synthesis: Employed as a building block in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Used to synthesize probes for studying biological processes and enzyme activities.
• Ligand and Catalyst Development: A precursor for synthesizing novel ligands and organometallic catalysts.

Basic Information

Product Name	Azidoacetic Acid Methyl Ester
CAS No.	1816-92-8
Molecular Formula	C3H5N3O2
Molecular Weight	115.09 g/mol
Synonyms	Methyl Azidoacetate; Azidoacetic Acid Methyl Ester; Methyl 2-Azidoacetate; 2-Azidoacetic Acid Methyl Ester; Azidoacetate Methyl Ester; Methyl Glycinate, N3-; Methyl Azidoethanoate
EINECS	217-333-8

Quality Control

Our Azidoacetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for optimal long-term stability. Due to its properties as an easily oxidized and highly volatile compound, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) and handle with appropriate precautions to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.435 - 1.445
Density (g/mL, 20°C)	1.15 - 1.25

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.