Description

Trifluoroacetic Acid 2,4-Dimethylphenyl Ester is a specialized organofluorine compound, an ester derivative of trifluoroacetic acid and 2,4-dimethylphenol. This chemical is valued for its role as a versatile intermediate and protecting group reagent in advanced synthetic chemistry. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoroacetyl or aryl ester protecting groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where its structural motifs confer specific biological activity.
• Peptide Chemistry: Serves as a reagent for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic materials with unique surface properties.
• Chemical Derivatization: Utilized in analytical chemistry to create volatile derivatives of complex molecules for GC-MS or LC-MS analysis.
• Cross-Coupling Reactions: Acts as a substrate or intermediate in palladium-catalyzed cross-coupling reactions for constructing biaryl systems.

Basic Information

Product Name	Trifluoroacetic Acid 2,4-Dimethylphenyl Ester
CAS No.	1814-00-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	2,4-Dimethylphenyl Trifluoroacetate; 2,4-Xylyl Trifluoroacetate; Trifluoroacetic Acid 2,4-Xylyl Ester; 2,4-Dimethylphenyl Ester of Trifluoroacetic Acid; α,α,α-Trifluoro-2,4-xylenol acetate; 2,4-DMPTFA; 1-Trifluoroacetyloxy-2,4-dimethylbenzene; (2,4-Dimethylphenoxy)carbonotrifluoride
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid 2,4-Dimethylphenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and moisture. Containers should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.