Description

(R)-1-Hydroxy-1-Phenylacetone is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of various APIs, including adrenergic drugs and other bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Research: Serves as a building block for developing chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific enantiomeric purity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	(R)-1-Hydroxy-1-Phenylacetone
CAS No.	1798-60-3
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(R)-1-Phenyl-1-hydroxy-2-propanone; (R)-α-Hydroxypropiophenone; (R)-1-Hydroxy-1-phenylpropan-2-one; (R)-HPP; (R)-1-Phenyl-2-propanone-1-ol; (R)-1-Hydroxy-1-phenylacetone; (R)-(-)-1-Hydroxy-1-phenyl-2-propanone; (R)-Phenylhydroxyacetone
EINECS	Contact for details

Quality Control

Our (R)-1-Hydroxy-1-Phenylacetone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.