Description

Trimethylsulfoxonium Iodide is a versatile organosulfur reagent widely used as a methylenation agent in organic synthesis. Its primary value lies in its ability to generate sulfur ylides for the synthesis of epoxides, cyclopropanes, and other strained ring systems from carbonyl compounds. This high-purity chemical is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking reliable and efficient synthetic pathways.

Application

• Corey-Chaykovsky Reaction: As a key reagent for the methylenation of aldehydes and ketones to produce epoxides (oxiranes).
• Cyclopropanation: For the synthesis of cyclopropane derivatives from α,β-unsaturated carbonyl compounds (Michael acceptors).
• Pharmaceutical Intermediates: In the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) requiring epoxide or cyclopropane motifs.
• Agrochemical Synthesis: Used in creating herbicides, fungicides, and insecticides with specific three-membered ring structures.
• Material Science Research: For the development of novel polymers and specialty chemicals with unique properties.
• Academic & Process R&D: A fundamental tool in methodological organic chemistry research and scale-up process optimization.

Basic Information

Product Name	Trimethylsulfoxonium Iodide
CAS No.	1774-47-6
Molecular Formula	C₃H₉IOS
Molecular Weight	220.07 g/mol
Synonyms	Trimethylsulfoxonium iodide; Sulfoxonium, trimethyl-, iodide; Trimethyloxosulfonium iodide; (Methanesulfinyl)trimethyl-λ⁵-sulfanuidyl iodide; TMSOI; Trimethylsulfonium oxide iodide
EINECS	217-207-1

Quality Control

Our Trimethylsulfoxonium Iodide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay by titration and identification by FT-IR and NMR spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets the rigorous standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Melting Point	208 - 212 °C (dec.)
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.