Description

5-Chloropyrrole-2-Carboxaldehyde is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. Its unique pyrrole core functionalized with both a chloro group and an aldehyde makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyrrole structure for bioactive molecule design.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers, organic semiconductors, and dyes due to its electron-rich pyrrole ring and reactive aldehyde group.
• Chemical Research & Development: Employed in academic and industrial R&D for heterocyclic chemistry, methodology development, and library synthesis for high-throughput screening.
• Ligand & Catalyst Preparation: The aldehyde functionality allows for the creation of Schiff base ligands used in coordination chemistry and catalysis.
• Fluorescent Probe & Sensor Development: Acts as a core structure for synthesizing fluorescent markers and chemosensors used in biochemical assays and diagnostics.

Basic Information

Product Name	5-Chloropyrrole-2-Carboxaldehyde
CAS No.	1757-28-4
Molecular Formula	C5H4ClNO
Molecular Weight	129.54 g/mol
Synonyms	5-Chloro-1H-pyrrole-2-carboxaldehyde; 5-Chloro-2-formylpyrrole; 2-Chloro-5-formylpyrrole; 5-Chloro-2-pyrrolecarboxaldehyde; 5-Chloropyrrole-2-aldehyde; 2-Pyrrolecarboxaldehyde, 5-chloro-; 5-Chloro-1H-pyrrole-2-carbaldehyde
EINECS	217-158-6

Quality Control

Our 5-Chloropyrrole-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.