Description

Ethyl 2,4,6-Trimethylbenzoate is a versatile aromatic ester characterized by its mesitylene-derived structure, serving as a key intermediate and building block in advanced organic synthesis. Its value lies in providing a sterically hindered benzoate moiety, which is crucial for modulating reactivity and physical properties in target molecules. This compound is essential for R&D chemists and production units in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sterically hindered ester groups for prodrug strategies or metabolic stability.
• Agrochemical Synthesis: Acts as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators where the trimethyl-substituted aromatic ring enhances lipophilicity and bioactivity.
• Organic Synthesis Building Block: Employed in research laboratories for constructing complex molecules, including ligands for catalysis, dyes, and polymers.
• Fragrance and Flavor Ingredient Intermediate: Utilized in the production of aroma chemicals, where its ester functionality and stable aromatic core contribute to specific olfactory notes.
• Material Science: Serves as a monomer or modifier in the synthesis of specialty polymers and resins to impart specific thermal or solubility characteristics.

Basic Information

Product Name	Ethyl 2,4,6-Trimethylbenzoate
CAS No.	1754-55-8
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	Ethyl Mesitoate; Ethyl 2,4,6-Trimethylbenzoate; Benzoic acid, 2,4,6-trimethyl-, ethyl ester; Ethyl 2,4,6-trimethylbenzenecarboxylate; Mesitoic Acid Ethyl Ester; NSC 404080; Ethyl trimethylbenzoate
EINECS	217-150-0

Quality Control

Our Ethyl 2,4,6-Trimethylbenzoate is produced under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support compliance with relevant frameworks for industrial and research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.