Description

5,6,7,8-Tetrafluorobenzo-1,4-Dioxane is a high-value, fluorinated heterocyclic compound with the CAS number 1743-87-9. This specialty chemical is a critical building block in advanced organic synthesis, prized for its unique electronic properties imparted by the tetrafluoro substitution on the aromatic ring. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Organic Light-Emitting Diode (OLED) Research: Investigated as an electron-transport material or host matrix in the development of next-generation display technologies.
• Ligand and Catalyst Development: The benzo-1,4-dioxane core can be functionalized to create novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) and the effects of polyfluorination on aromatic systems.

Basic Information

Product Name	5,6,7,8-Tetrafluorobenzo-1,4-Dioxane
CAS No.	1743-87-9
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	Benzo-1,4-dioxane, 5,6,7,8-tetrafluoro-; 5,6,7,8-Tetrafluoro-1,4-benzodioxane; 1,4-Benzodioxane, 5,6,7,8-tetrafluoro-; Tetrafluorobenzodioxane; 1743-87-9; 5,6,7,8-Tetrafluorobenzo[1,4]dioxane; 5,6,7,8-Tetrafluoro-2,3-dihydro-1,4-benzodioxin
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrafluorobenzo-1,4-Dioxane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.