Description

Benzyl L-Leucinate is a protected amino acid derivative, specifically the benzyl ester of the essential amino acid L-Leucine. This compound serves as a crucial chiral building block and intermediate in the synthesis of complex peptides, pharmaceuticals, and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, protease inhibitors, and other therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected leucine residue, where the benzyl ester group can be selectively removed.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway research, and as a substrate for esterase activity assays.
• Fine Chemical Production: An intermediate in the manufacture of flavors, fragrances, and specialty chemicals requiring high optical purity.
• Agrochemical Development: Used in the research and synthesis of novel pesticides and herbicides that incorporate amino acid motifs.

Basic Information

Product Name	Benzyl L-Leucinate
CAS No.	1738-69-8
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	L-Leucine benzyl ester; (S)-2-Amino-4-methylpentanoic acid benzyl ester; Benzyl (S)-2-amino-4-methylpentanoate; H-Leu-OBzl; Leucine benzyl ester; Bzl-Leu-OH; Benzyl leucinate; L-Leucine, benzyl ester
EINECS	217-099-6

Quality Control

Our Benzyl L-Leucinate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.