Description

3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarboxylic Acid is a high-purity fluorinated isoxazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole moiety.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced materials with specific optical or electronic properties.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a core structure in fragment-based drug discovery.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services and contract research organizations (CROs) producing bespoke compounds for client projects.

Basic Information

Product Name	3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarboxylic Acid
CAS No.	1736-21-6
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	5-Methyl-3-(4-fluorophenyl)-4-isoxazolecarboxylic acid; 4-Isoxazolecarboxylic acid, 3-(4-fluorophenyl)-5-methyl-; 3-(p-Fluorophenyl)-5-methyl-4-isoxazolecarboxylic Acid; 3-(4-Fluorophenyl)-5-methylisoxazole-4-carboxylic acid; 1736-21-6; 4-Carboxy-3-(4-fluorophenyl)-5-methylisoxazole; 5-Methyl-3-(4-fluorophenyl)isoxazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.