Description

Trifluoroacetic Acid 3-Methylphenyl Ester is a specialized fluorinated aromatic ester derived from trifluoroacetic acid. This compound is valued for its role as a versatile building block and reagent in advanced organic synthesis, particularly where the introduction of a trifluoroacetyl group is required. It is primarily utilized by pharmaceutical intermediates, agrochemical, and specialty chemical manufacturers for research and production processes.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for introducing the trifluoromethyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorination enhances biological activity and environmental persistence.
• Organic Synthesis Building Block: Serves as an acylating agent and protecting group in complex multi-step synthetic routes for fine chemicals and material science.
• Liquid Crystal & Electronic Chemical Precursor: Employed in the manufacture of fluorinated compounds for electronic materials and liquid crystal displays (LCDs).
• Research & Development: A critical tool in medicinal chemistry and process development labs for exploring new chemical entities and optimizing synthetic pathways.

Basic Information

Product Name	Trifluoroacetic Acid 3-Methylphenyl Ester
CAS No.	1736-09-0
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-Methylphenyl Trifluoroacetate; m-Tolyl Trifluoroacetate; Trifluoroacetic Acid m-Tolyl Ester; α,α,α-Trifluoro-m-cresyl Acetate; 3-Methylphenyl Trifluoroethanoate; m-Cresyl Trifluoroacetate; TFA 3-Methylphenyl Ester; 1-Trifluoroacetyl-3-methylbenzene
EINECS	217-085-8

Quality Control

Our Trifluoroacetic Acid 3-Methylphenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are kept tightly sealed to prevent moisture ingress and evaporation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear Colorless to Pale Yellow Liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.