Description

1-Chloro-3-Nitro-Propan-2-Ol is a versatile halogenated nitro alcohol intermediate of significant importance in fine chemical synthesis. Its unique bifunctional structure, featuring both a reactive chloro and a nitro group on a propanol backbone, makes it a valuable building block for constructing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing β-amino alcohol or nitroalkane motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its reactive groups allow for the introduction of specific functional activity.
• Organic Synthesis Building Block: Employed in research and development for creating complex organic molecules, including heterocycles, via nucleophilic substitution or reduction reactions.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for modifying polymer properties such as adhesion, solubility, or reactivity.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized dyes and colorants due to the nitro group's electron-withdrawing properties.

Basic Information

Product Name	1-Chloro-3-Nitro-Propan-2-Ol
CAS No.	1713-83-3
Molecular Formula	C₃H₆ClNO₃
Molecular Weight	139.54 g/mol
Synonyms	2-Chloro-1-(hydroxymethyl)-2-nitroethanol; 3-Chloro-1-nitro-2-propanol; 1-Chloro-3-nitro-2-propanol; 2-Nitro-3-chloro-1-propanol; 3-Chloro-2-hydroxy-1-nitropropane; NSC 402124; β-Chloro-β-nitroisopropanol
EINECS	217-001-7

Quality Control

Our 1-Chloro-3-Nitro-Propan-2-Ol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.