Description

Isothiazole-5-Methanol is a versatile heterocyclic building block and intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both an isothiazole ring and a hydroxymethyl functional group, makes it a valuable precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This compound is particularly sought after by research and development teams in the pharmaceutical industry for creating novel active ingredients, as well as by manufacturers of specialty chemicals and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antimicrobial, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its bioactive heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Research & Development: A fundamental building block for exploring new chemical entities and reaction pathways in academic and industrial R&D laboratories.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	Isothiazole-5-Methanol
CAS No.	1710-66-3
Molecular Formula	C4H5NOS
Molecular Weight	115.15 g/mol
Synonyms	5-(Hydroxymethyl)isothiazole; 5-Isothiazolemethanol; 1,2-Thiazol-5-ylmethanol; Isothiazol-5-ylmethanol; 5-Hydroxymethylisothiazole; (Isothiazol-5-yl)methanol; 5-Methanolisothiazole
EINECS	216-968-6

Quality Control

Our Isothiazole-5-Methanol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.