Description

4-Hydroxy-8-Methyl-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its unique trifluoromethyl and hydroxyl substituents. This compound is critical for advanced research and development, offering a versatile scaffold for creating novel molecules with tailored properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in drug discovery, crop protection, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and anti-infective applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the quinoline and trifluoromethyl groups.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transporting or host material in the fabrication of OLED devices due to its favorable electronic properties and thermal stability.
• Coordination Chemistry & Catalysis: Functions as a chelating ligand for transition metals, forming complexes used in catalytic reactions and material science.
• Fluorescent Probe Synthesis: Utilized as a core structure for developing sensitive fluorescent dyes and sensors for biological and chemical detection.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists exploring novel heterocyclic reactions and structure-activity relationships.

Basic Information

Product Name	4-Hydroxy-8-Methyl-2-(Trifluoromethyl)Quinoline
CAS No.	1701-19-5
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	8-Methyl-2-(trifluoromethyl)quinolin-4-ol; 2-(Trifluoromethyl)-8-methyl-4-quinolinol; 4-Hydroxy-8-methyl-2-trifluoromethylquinoline; 4-Quinolinol, 8-methyl-2-(trifluoromethyl)-; 1701-19-5; Quinoline, 4-hydroxy-8-methyl-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-8-Methyl-2-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.