Description

2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity fused pyrimidine derivative, serving as a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry. Its unique heterocyclic structure makes it a valuable building block for the synthesis of novel bioactive compounds targeting a range of therapeutic areas. This compound is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides due to its bioactive pyrimidine core.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and other heterocyclic compounds.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1693-94-3
Molecular Formula	C9H8N2O
Molecular Weight	160.17 g/mol
Synonyms	2-Methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 2-Methylpyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 2-methyl-; NSC 102627; 2-Methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine; 2-Methylpyrido[1,2-a]pyrimidin-4(1H)-one
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is produced under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for research and development applications. A detailed Certificate of Analysis (COA) with specifications for assay (HPLC), related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.