Description

1-Methyl-3-Methylenepiperidin-2-One is a versatile heterocyclic building block featuring a reactive methylene group adjacent to a lactam carbonyl. This compound is valued for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its piperidinone core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocycles via reactions at its exocyclic methylene group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a monomer or additive in the development of specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1-Methyl-3-Methylenepiperidin-2-One
CAS No.	1690-73-9
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	3-Methylene-1-methyl-2-piperidinone; 1-Methyl-3-methylenepiperidin-2-one; 3-Methylene-1-methylpiperidin-2-one; 2-Piperidinone, 3-methylene-1-methyl-; 1-Methyl-3-methylen-2-piperidon; NSC 163044
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Methylenepiperidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Specifications can be developed to meet cGMP or other stringent regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.